Joint Replacement & Bone Resorption

<P>The first guide devoted to this burgeoning topic, this authoritative reference presents current understanding of the phenomenon of aseptic loosening of total joint replacements, from the molecular and cellular mechanisms of periprosthetic bone loss to the clinical presentation and management strategies. Reviewing the properties of ceramic, metal, and polymer materials used in the replacement of joints, it also discusses current research on bone remodeling, wear resistance, the long-term care of implants, and emerging developments in gene therapy and tissue engineering.</P> <P>Written by eminent surgeons and scientists at the front-lines of orthopedic surgery and research, this guide:</P> <P>* explains key opportunities in genomics and proteomics, which can be used to enhance the understanding of patient variables associated with the failure of joint replacements</P> <P>* summarizes the essential engineering principles of joint replacements, such as properties of biomaterials, wear and its sequelae, corrosion, and the fixation of implants</P> <P>* provides critical assessment of the different causes of osteolysis around implants.</P>
ISBN: 978-0-8247-2954-7

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